The lecture teaches central reactions and metabolic pathways of biochemistry as well as molecular biology with emphasis on chemical and partly biophysical aspects.

The school (1.9. - 12.9.2008) will discuss the recent progress and challenges in biological and medical imaging. Cutting edge techniques using a wide range of imaging mechanisms will be put in the context of selected biomedical problems. In particular, multimodal and multiscale imaging methods as well as supporting technologies such as computer aided image analysis and modeling will be discussed.

Many viruses have evolved specialized mechanisms to hijack the host gene expression machinery and employ cellular resources to regulate viral life cycle. They accomplish this through producing non-structural proteins that can, among other things, inhibit host protein synthesis. Participants of this course will visualize ribosomes in complex with a non-structural viral protein at high resolution.

This 1st year Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. During this course (Praktikum GL BioI) the students will do three praktikum days in:- Biochemistry- Cell Biology I- Microbiology- Plant Anantomy & Ecology(total of 12 experiments)Each experiment takes one full day.

The lecture provides an introduction to the basics of biochemistry and molecular biology as well as evolutionary principles. The focus is on bacteria and archaea under consideration of universal concepts.

Amino acids; structure of proteins; folding; dynamics and evolution; protein purification; sugars and polysaccharides; lipids and membranes. Enzymatic catalysis. Metabolism; Gene expression and propagation of genetic information; structure of DNA; ; transcription; protein biosynthesis; DNA replication. Gene technology; production of recombinant proteins

The course provides an introduction to Biochemistry / Molecular Biology with some emphasis on chemical and biophysical aspects.

The course provides an introduction to Biochemistry / Molecular Biology with some emphasis on chemical and biophysical aspects.

The lecture provides an introduction to the function and regulations of cells.

This Concept Course explores the molecular and structural mechanisms underlying key processes in gene expression and protein biogenesis. The course will present advanced mechanistic aspects of the organization and regulation of chromatin, transcription, RNA maturation, translation, and the pathways of protein folding, modification, trageting to membranes, and quality control.

Mechanisms of biomacromolecular recognition. The basics of protein, DNA and RNA structures and their complexes are described, with special emphasis on functionality and energetic aspects.

The course consists of a series of research seminars on Structural Biology and Biophysics, given by both scientists of the National Center of Competence in Research (NCCR) in Structural Biology and external speakers.

This course on advanced topics in molecular biology and biochemistry covers the structure and function of large cellular protein assemblies. The lecturers will cover topics including membrane proteins, protein glycosylation, horizonal gene transfer, microbial cytomotive filaments, and microbial contractile injection systems.

This course provides an in-depth discussion of two main methods to determine the 3D structures of macromolecules and complexes at high resolution: X-ray crystallography and cryo-electron microscopy. Both techniques result in electron density maps that are interpreted by atomic models.

The course consists of a series of research seminars on Structural Biology, Biochemistry and Biophysics, given by both scientists of the National Center of Competence in Research (NCCR) in Structural Biology and external speakers. Information on the individual seminars is provided on the following websites:http://www.structuralbiology.uzh.ch/educ002.asphttp://www.biol.ethz.ch/dbiol-cal/index

This course covers aspects of RNA biology related to gene expression at the posttranscriptional level. These include RNA transcription, processing, alternative splicing, editing, export and translation.