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551-0125-00L 6 Credits BSC D-BIOL , D-CHAB

Fundamentals of Biology I: From Molecules to the Biochemistry of Cells

Grundlagen der Biologie I: von Molekülen zur Biochemie der Zellen

VVZ CR 4.0

Last Updated: 2026-06-03 00:07:29

Abstract

The lecture provides an introduction to the basics of biochemistry and molecular biology as well as evolutionary principles. The focus is on bacteria and archaea under consideration of universal concepts.

Objective

Introduction to biochemistry, molecular biology and evolutionary principles

Content

The lecture introduces biology as an interdisciplinary science. Links to physics and chemistry will manifest as biological processes that operate within the laws of thermodynamics and are rooted in elements, molecules and chemical reactions. The transition from geochemistry to biochemistry is discussed and considered in relation to the origin of life. Evolutionary principles are introduced and resulting processes are used as a guiding principle. Unifying concepts in biology are presented, including the structure and function of cellular macromolecules and the ways in which hereditary information is encoded, decoded and replicated. Central principles of universal energy conversion are looked at, starting from redox processes and focusing on bacteria and archaea. Finally, biological processes are put into an ecosystems perspective. The lecture is divided into different sections: 1. Geochemical perspectives on Earth and introduction to evolution 2. Building blocks of life 3. Macromolecules: Proteins 4. Membranes and transport across the plasma membrane 5. Universal mechanisms of inheritance, transcription and translation 6. Reaction Kinetics, binding equilibria and enzymatic catalysis 7. Essentials of Catabolism 8. Essentials of Anabolism 9. Metabolism and biogeochemical cycling of elements

Resources

Lecture Notes

The course is supported by a new textbook, “From Molecules to the Biochemistry of Cells”, and a handout.

Literature

Julia A. Vorholt, Jörn Piel, Markus Aebi, Donald Hilvert, «From Molecules to the Biochemistry of Cells» 2026, CRC Press

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 150 minutes
Aids
Einfacher Taschenrechner
Digital
The exam takes place on devices provided by ETH Zurich.
Die Prüfungsfragen werden auf Deutsch und Englisch gestellt und können in beiden Sprachen beantwortet werden.

Course Components

Type Title Time & Place Hours
lecture with exercise Grundlagen der Biologie I: von Molekülen zur Biochemie der Zellen
Vorlesung: Montag 11:45-13:30 Uhr, Donnerstag 9:45-11:30 Uhr Übungen: Freitag 11:45-12:30 Uhr oder 12:45-13:30 Uhr Gastvorlesung 17.09.2026 15:45-17:30 Uhr
No time listed 5 h weekly

Offered In