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Molecular and Structural Biology I: Molecular Mechanisms of Gene Expression and Protein Biogenesis
Last Updated: 2026-06-01 11:30:37
Abstract
This Concept Course explores the molecular and structural mechanisms underlying key processes in gene expression and protein biogenesis. The course will present advanced mechanistic aspects of the organization and regulation of chromatin, transcription, RNA maturation, translation, and the pathways of protein folding, modification, trageting to membranes, and quality control.
Objective
Students will develop a mechanistic and structural understanding of how complex cellular processes - such as transcription, translation, and protein folding - are orchestraded by large molecular assemblies. The course aims to develop analytical thinking through in-depth discussions of selected research studies. By the end of the course, students will be able to critically evaluate experimental strategies and structural insights that drive our current understanding of molecular cell biology.
Resources
Lecture Notes
The material used in the course can be found on Moodle (link see "Learning materials").
Literature
Basics: - Creighton, T.E., Proteins, Freeman, (1993) - Fersht, A., Enzyme, Structure and Mechanism in Protein Science (1999), Freeman. - Berg, Tymoczko, Stryer: Biochemistry (5th edition), Freeman (2001). Current topics: References will be given during the lectures. .
Learning Materials (Links)
- Moodle course
- Moodle-Kurs / Moodle course
General Information
- Language
- English
- Levels
- BSC , MSC , NDS
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- written 75 minutes
- Aids
- a simple non-programmable calculator
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture | Molecular and Structural Biology I: Molecular Mechanisms of Gene Expression and Protein Biogenesis |
|
2 h weekly |
Offered In
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Wahlpflicht Konzeptkurse (Siehe D-BIOL Master-Wegleitung)
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Wahlpflicht Konzeptkurse (Siehe D-BIOL Master-Wegleitung)
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Computational Biology and Bioinformatics Master (Weitere Informationen: )
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Vertiefungsfächer (In den Vertiefungsfächern müssen insgesamt 30 ECTS erworben werden. Davon mindestens 16 ECTS in der Unterkategorie Theorie und mindestens 10 ECTS in der Unterkategorie Biologie.)
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Biologie (Mindestens 10 ECTS müssen in dieser Unterkategorie erworben werden.)
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