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551-0102-00L 5 Credits
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Fundamentals of Biology IB: Molecular biology and Biochemistry

GL der Biologie IB: Molekularbiologie und Biochemie

Lecturers: Prof. em. Dr. Peter Dimroth, Prof. em. Dr. Rudolf Glockshuber, Prof. em. Dr. Donald Hilvert, Prof. em. Dr. Fritz K. Winkler, Prof. em. Dr. Wilhelm Gruissem, Prof. Dr. Nenad Ban, Prof. Dr. Frédéric Allain, Prof. Dr. Matthias Peter
Examiners: Prof. em. Dr. Peter Dimroth, Prof. em. Dr. Rudolf Glockshuber, Prof. em. Dr. Donald Hilvert, Prof. em. Dr. Wilhelm Gruissem, Prof. Dr. Nenad Ban, Prof. Dr. Frédéric Allain
VVZ CR n/a

Last Updated: 2026-02-05 15:02:27

Abstract

Amino acids; structure of proteins; folding; dynamics and evolution; protein purification; sugars and polysaccharides; lipids and membranes. Enzymatic catalysis. Metabolism; Gene expression and propagation of genetic information; structure of DNA; ; transcription; protein biosynthesis; DNA replication. Gene technology; production of recombinant proteins

Objective

Knowledge on the structural construction of biological macromolecules, principles of enyme catalysed reactions, basics of molecular genetics and protein biochemistry, basic mechanisms of metabolism and of DNA replication and gene expression.

Content

Part 1: Biomolecules; amino acids; covalent assembly of proteins; three dimensional structure of proteins; folding; dynamics and evolution of proteins; methods of protein purification; sugars and polysaccharides; lipids and membranes. Part 2: Enzymatic catalysis: classes of enzymes; kinetics of non catalysed versus catalysed reactions. Examples for the mechanisms of enzyme catalysis. Part 3: Metabolism: Principles of metabolic pathways in living cells; glycolysis; glycogen metabolism; mechanisms of membrane transport; citric acid cycle; electron transport and oxidative phosphorylation. Part 4: Gene expression and propagation of genetic information; structure of DNA; DNA modifying enzymes and manupulation of nucleic acids; transcription; protein biosynthesis; DNA replication. Part 5: Gene technology; production of recombinant proteins

Resources

Lecture Notes

Available in part, e.g. underwww.micro.biol.ethz.ch

Literature

"Biochemistry" (Voet & Voet; Wiley & Sons, 2nd edition).

General Information

Language
German
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 150 minutes
Aids
Nicht-programmierbarer Taschenrechner.

Course Components

Type Title Time & Place Hours
lecture GL der Biologie IB: Molekularbiologie und Biochemie
  • Mon 13:15-15:00 (ETA F 5)
  • Tue 15:15-17:00 (ETA F 5)
  • Fri 11:15-12:00 (ETA F 5)
5 h weekly

Offered In