The school (1.9. - 12.9.2008) will discuss the recent progress and challenges in biological and medical imaging. Cutting edge techniques using a wide range of imaging mechanisms will be put in the context of selected biomedical problems. In particular, multimodal and multiscale imaging methods as well as supporting technologies such as computer aided image analysis and modeling will be discussed.

The lecture teaches the most important fundamental concepts in chemistry (atomic structure, chemical bonds, thermodynamics and kinetics of chemical reactions, acid-base equilibria, types and reactivity of organic compounds, stereochemistry, biomolecules). Connections of chemical processes with medically important biochemical, physiological, and pharmacological questions are highlighted.

This course provides an overview over the concepts and processes employed in today's drug discovery and development. It has an introductory character but will also provide more detailed insights employing real life examples. The course combines lectures and interactive elements which require active participation of the students.

The course provides a platform for the investigation, presentation and discussion of a topic with relevance to the field of pharmaceutical sciences. Students work in small groups on a chosen topic and present their work on a one day symposium.

First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities.

The essay is an essential part of the CAS program „Pharmaceuticals – From Research to Market“ (CAS Pharm) and serves as final performance assessment.

The lecture series takes place at the ETH Hönggerberg and covers a variety of major activities involved in drug discovery: selecting drug targets, technologies used in drug discovery, small, medium and large drugs, objectives of the medicinal chemist, assessing drug safety, principles of personalized medicine, designing clinical trials, how intellectual property is protected, as well as others.

First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities.

Solving analytical problems; Development and interpretation of analytical methods.

The course introduces the foundations of noninvasive imaging including X-ray imaging, Computed Tomography, Magnetic Resonance Imaging, Single Photon and Positron Emission Tomography, Ultrasound and Optical Imaging. Besides the physical and technical methodology, the assessment of imaging performance is covered to enable students to identify relative advantages and limitations.

Transition metals and their corresponding complexes are often ignored in the classical drug development process. This is in sharp contrast to the fact, that among the 100 stable elements, 2/3 are metals or possess inherent metallic character. Their rich and diverse chemistry potentially provide access to novel compounds with different chemical and structural features useful in medicine.

Students learn about the different health systems, primarily about the European and the Swiss specialities, then also in comparison with the US system. A short introduction is made about Marketing with focus on Pharma, the legislation and patents/licencing are discussed and pharmacooeconomic aspects and business development are explained and intensified through workshops.

In this module, students learn to plan, execute, and manage pharma industry projects effectively, emphasizing clear objectives and timelines. They develop skills in team collaboration, conflict resolution, and stakeholder communication to ensure project success. Students also enhance their ability to convey ideas clearly and persuasively to diverse audiences through role-playing exercises.

Students learn about pharmaceutical regulations in Switzerland, EU and US, various quality systems and CAPA, quality risk management, life cycle management, quality assurance of biotechnological processis, process validation, quality by design, statistical tools in QA, computerized systems validation, quality aspects of packaging and the role of the qualified person.

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Students learn about the pharmaceutical drug development process from the analytical characterisation of drug product both for small molecules and biotechnological drug substandes. The learnings include: formulation of clinical and market form, scale-up, 2D/3D printing technology for drugs, clinical trial supply, commercial packaging, supply chain management and continuous manufacturing.

Students learn about the regulatory aspects of drug development, about the Swiss, European and FDA regulations, regulatory information and strategies, personalizing healthcare and the role of companion diagnostics, about special regulations for biosimilars, medical devices, generics, orphan drugs, GMOs and advanced therapeutics incl. gene therapy and pharmacovigilance.

This module gives an overview about the several steps that have to be followed during the process of clinical development.

Knowledge of the fundamentals of development, preparation, testing and stability of sterile radiopharmaceutical preparations.Acquirement of basic information on European legislation in Radiopharmacy including GMP and Pharmacopoeia.Understanding basics of gene engineering and pharmacokinetics

Knowledge about the fundamentals of radionuclide production and generator systems, design and in vitro-& in vivo-characterization of radiolabelled peptides and antibodies., chemistry of Tc, Re and other radiometals, including the usage of kits as well as of chemistry of 11C and 18F and of other radiohalogens.