Fundamentals of selective organic reactions, including current and historical examples of enantioselectivity, regioselectivity, chemoselectivity. Further aspects include recent developments in catalysis, strategies and tools for selective organic synthesis.

In the General Chemistry Practical Course, students are introduced to the work in a modern chemistry laboratory. Conceptually, the course addresses three major topics: (i) inherent risks in the chemistry laboratory, (ii) common equipment and techniques, (iii) basic classes of reactions and chemical equilibrium.

Organic synthesis; purification of organic substances by recrystallization, distillation, column chromatography, and extraction; characterization of organic substances using IR-spectroscopy, thin-layer chromatography, and melting point analysis; writing scientifically accurate reports.

Practical Introduction to Experimental Methods in Analytical and Bioanalytical Chemistry

Organic synthesis; purification of organic substances by recrystallization, distillation, column chromatography, and extraction; characterization of organic substances using IR spectroscopy, thin-layer chromatography, and melting point analysis; writing scientifically accurate reports.

An organic-synthetic sub-project of the current research of a group from the Laboratory of Organic Chemistry is carried out under the guidance of doctoral students.

This course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. The basics or retro- and forward synthesis are also introduced.

The synthesis and reactivity of organic molecules plays a crucial role in chemical biology, particularly for the interrogation of biological pathways and phenomena. This course will cover advanced topics in the design and synthesis of organic molecules for applications in biochemistry and chemical biology, with particular emphasis on the mechanistic understanding of these reactions and processes.

In this block course we will prepare proteins carrying electrophilic groups to interrogate intracellular pathways. These probes will be prepared by recombinant protein expression & purification followed by site-specific protein modification with electrophilic probes. Their reactivity will be tested in mammalian whole cell lysates and analyzed by proteolytic digestion and tandem mass spectrometry.