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529-0241-10L 6 Credits MSC D-BIOL , D-CHAB

Selectivity in Organic Synthesis

Lecturers & Examiners: Prof. Dr. Jeffrey W. Bode, Dr. Jessada Mahatthananchai
VVZ CR n/a

Last Updated: 2026-06-03 00:07:29

Abstract

Fundamentals of selective organic reactions, including current and historical examples of enantioselectivity, regioselectivity, chemoselectivity. Further aspects include recent developments in catalysis, strategies and tools for selective organic synthesis.

Objective

Understanding and explaining the origin of selectivity in organic synthesis and the application of selective organic reactions to the construction of complex organic and biological molecules.

Content

Fundamental concepts and recent advances for the selective synthesis of complex organic molecules, including natural products, pharmaceuticals, and biological molecules. Key concepts include the development of enantioselective and regioselective catalysts, the identification of new reaction mechanisms and pathways, and technological advances for facilitating the synthesis of organic molecules. Analysis of key primarily literature including identification of trends, key precendents, and emerging topics will be emphasized.

Resources

Lecture Notes

will be provided in class and online

Literature

Suggesting Textbooks Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books, 2006.

General Information

Language
English
Levels
MSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 90 minutes
Aids
keine
Students will be assigned a relevant, recent paper from the primary literature, which will be used as the basis for a presentation and discussion at the oral examination. This paper will serve as a starting point for a scientific discourse that covers the fundamental concepts taught in the course, including the origin of selectivity, reaction mechanisms, the synthesis of organic molecules, and the application of new technologies and concepts to facilitating organic synthesis.

Course Components

Type Title Time & Place Hours
lecture with exercise Selectivity in Organic Synthesis
Lecture: 12-14 Exercises: 15–16
No time listed 3 h weekly

Offered In