This course provides an overview of modern concepts of bioengineering across different levels of complexity, from single molecules to systems, microscaled reactors to production environments, and across different fields of applications

This course provides an overview of modern concepts of bioengineering across different levels of complexity, from single molecules to systems, microscaled reactors to production environments, and across different fields of applications

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Biological Engineering and Biotechnology will cover the latest biotechnological advances as well as their industrial implementation to engineer mammalian cells for use in human therapy. This lecture will provide forefront insights into key scientific aspects and the main points in industrial decision-making to bring a therapeutic from target to market.

Biological Engineering and Biotechnology will cover the latest biotechnological advances as well as their industrial implementation to engineer mammalian cells for use in human therapy. This lecture will provide forefront insights into key scientific aspects and the main points in industrial decision-making to bring a therapeutic from target to market.

Diversity of microbial metabolism, adaptation of cells to changing parameters, post-translational events, intervention in the metabolism, expression technologies for prokaryotic and eukaryotic hosts, gene expression in transgenic plants and animals, gene therapy, cell-culture technology, production of products, production processes, calculation of costs and economic aspects.

Diversity of microbial metabolism, adaptation of cells to changing parameters, post-translational events, intervention in the metabolism, expression technologies for prokaryotic and eukaryotic hosts, gene expression in transgenic plants and animals, gene therapy, cell-culture technology, preparation of various products, production processes, cost calculations and economic aspects.

This seminar will feature invited lectures about recent advances and developments in systems biology, including topics from biology, bioengineering, and computational biology.

This introductory Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. In the second year (Praktikum GL Bio II) the students will perform three praktikum days in:- Bioinformatics- Plant Physiology- Genetics and- Cell Biology II.(total of 12 experiments)Each experiment takes one full day.

Mammalian cells will be transfected and transduced for the production of biopharmaceuticals, for drug discovery as well as for the design of synthetic biology-inspired programmable gene circuits. A wide array of analytical techniques, lectures, and excursions to biotech companies will complement the practical part.

Cultivation of human and animal cells, expression of various genes in animal cell lines, investigation of regulated gene expression, analysis of the cell cycle in cell lines used for production (under various culture conditions), reactor techniques and production of pharmaceutical proteins on an industrial scale, computer simulation for the analysis of biological and industrial processes.

Mammalian cells will be transfected and transduced with viral vectors for production of biopharmaceuticals, for generation of artificial microtissues, as vectors in gene/cell therapy studies, for drug discovery as well as for construction of synthetic biologic gene networks. A wide array of analytical techniques, lectures and excursions to biotech companies will complement the practical part.