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636-0108-00L 4 Credits MSC , NDS D-HEST , D-MAVT , D-INFK , D-PHYS , D-ITET , D-CHAB , D-BIOL , D-BSSE

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Biological Engineering and Biotechnology

Lecturers & Examiners: Prof. Dr. Martin Fussenegger

Attention: This course was offered in previous semesters with the number: 636-0003-00L "Biological Engineering and Biotechnology". Students that already passed course 636-0003-00L cannot receive credits for course 636-0108-00L.

VVZ CR n/a

Last Updated: 2026-02-05 15:36:13

Abstract

Biological Engineering and Biotechnology will cover the latest biotechnological advances as well as their industrial implementation to engineer mammalian cells for use in human therapy. This lecture will provide forefront insights into key scientific aspects and the main points in industrial decision-making to bring a therapeutic from target to market.

Objective

Content

1. Insight Into The Mammalian Cell Cycle. Cycling, The Balance Between Proliferation and Cancer - Implications For Biopharmaceutical Manufacturing. 2. The Licence To Kill. Apoptosis Regulatory Networks - Engineering of Survival Pathways To Increase Robustness of Production Cell Lines. 3. Everything Under Control I. Regulated Transgene Expression in Mammalian Cells - Facts and Future. 4. Secretion Engineering. The Traffic Jam getting out of the Cell. 5. From Target To Market. An Antibody's Journey From Cell Culture to The Clinics. 6. Biology and Malign Applications. Do Life Sciences Enable the Development of Biological Weapons? 7. Functional Food. Enjoy your Meal! 8. Industrial Genomics. Getting a Systems View on Nutrition and Health - An Industrial Perspective. 9. IP Management - Food Technology. Protecting Your Knowledge For Business. 10. Biopharmaceutical Manufacturing I. Introduction to Process Development. 11. Biopharmaceutical Manufacturing II. Up- stream Development. 12. Biopharmaceutical Manufacturing III. Downstream Development. 13. Biopharmaceutical Manufacturing IV. Pharma Development.

Resources

Lecture Notes

Handout during the course.

General Information

Language: English
Levels: MSC , NDS
Frequency: Yearly recurring

Examination

Type: session examination
Mode: written 60 minutes
Aids: keine

The written examination of this course will take place in Basel.

Course Components

Type	Title	Time & Place	Hours
lecture	Biological Engineering and Biotechnology Attention: Lecture starts on Wednesday, September 23 Lecture takes place in Basel, room Misrock (BSA E46) and is being streamed via Zoom, most of the lectures will also be recorded. The number of seats in the classroom is limited to 22. Students of the D-BSSE master programmes are prioritized. If you plan to attend the course in classroom in Basel, please send an email to: The written examination of this course will take place in Basel.	Wed 13:15-16:00 (BSA E 46)	3 h weekly

Offered In

Chemistry Master
- Electives (Students are free to choose from a range of D-CHAB chemistry courses appropriate to their level of study (please note admission requirements). In case of doubt, contact the student administration.)
  - Chemical Technology
Chemical and Bioengineering Master
- Electives
  - Biochemical Engineering
Biomedical Engineering Master
- Track Courses
  - Biomechanics
    - Recommended Elective Courses (These courses are particularly recommended for the Biomechanics track. Please consult your track advisor if you wish to select other subjects.)
  - Bioelectronics
    - Recommended Elective Courses (These courses are particularly recommended for the Bioelectronics track. Please consult your track advisor if you wish to select other subjects.)
  - Molecular Bioengineering
    - Track Core Courses (During the Master programme, a minimum of 12 CP must be obtained from track core courses.)
Biology Master
- Elective Major Subject Areas
  - Elective Major: Biochemistry
    - Elective Compulsory Master Courses
  - Elective Major: Biological Chemistry
    - Elective Compulsory Master Courses
  - Elective Major: Molecular Health Sciences
    - Elective Compulsory Master Courses (See D-BIOL Master Studies Guide)
MAS in Medical Physics
- Specialisation in General Medical Physics
Computational Biology and Bioinformatics Master (More informations at: )
- Advanced Courses (A total of 30 ECTS needs to be acquired in the Advanced Courses category. Thereof 18 ECTS in the Theory and 12 ECTS in the Biology category. Note that some of the lectures are being recorded: )
  - Biology (At least 12 ECTS need to be acquired in this category.)
Health Sciences and Technology Master
- Major in Medical Technology
  - Elective Courses
- Major in Molecular Health Sciences
  - Elective Courses
Biotechnology Master
- Advanced Courses (Students need to aquire a total of 24 ECTS in this category. The list of advanced courses is a closed list, no other course can be added to this category.)
  - Biomelecular-Orientated
  - System-Orientated