The focus of part I of the case study course lies on the literature-based comparison of chemical process alternatives. Based on this compilation and selected quantitative as well as qualitative measures, a process assessment and comparison is conducted. A basic flowsheet is then generated, and mass and energy balances are performed to carry out a preliminary economic and environmental assessment.

Based on part I of the case study course the main reaction and purification steps of one process alternative are investigated. Models describing the different unit operations have to be built. These models are used for a sensitivity analysis and optimization of the operating conditions. The results are discussed with regard to technical, economic, safety, and environmental implications.

A chemical process is investigated using one or several simulation programs. A cost calculation has to be implemented considering investment and operating cost. Afterwards sensitivity analyses and optimizations are conducted considering technical and in particular economic criteria.

Intoduction to the main specific areas in chemical and biochemical engineering. The students sharpen their laboratory skills and learn to plan and perform problem-oriented experiments and to analyse, interpret and present the results.

Application of methods for chemical risk assessment for human health and the environmental according to European regulation; hazard and risk; exposure and effect analysis for different types of chemicals. Estimation of missing chemical properties (QSAR methods); critical evaluation of risk assessment methods, presentation of alternative assessment methods.

Toxicokinetic and toxicodynamic aspects of xenobiotic interactions with cellular structures and mechanisms. Toxic responses at the level of organs (immune-, neuro-, reproductive and genotoxicity) and organisms. Introduction into developmental toxicology and ecotoxicology.

This course covers fundamentals as wells as applications of chemical process simulation and flowsheeting. It gives an introduction to steady-state and dynamic simulation techniques and flowsheeting software. The case studies used in the exercises range from single unit operations to complete chemical processes.

This module provides an overview of safety in the chemical industry, focusing on toxicology, industrial hygiene, fires and explosions, hazards identification and risk assessment. It also introduces the fundamentals of environmental impact studies, focusing on life cycle assessment.

Projects on chemical assessment with the focus on the analysis and assessment of basic substance data for selected chemical classes; analysis and modelling of technical processes; characterisation of environmental and health risks. Risk assessment on the basis of quality and protection goals. Estimation of model and parameter uncertainty. Precaution and safety measures.

Basic understanding of methodology and application of Product Risk Analysis, Process Risk and Life Cycle Assessment of chemicals.