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Gene Technology
Gentechnologie
Last Updated: 2026-02-05 15:24:51
Abstract
The aim of the lecture course is to provide a solid overview of the science and issues in gene technology and genome science. Topics:Antibody phage technology, protein modification technology, genome projects, genome sequencing, transcriptomics, proteomics and SNP technology. The course is suited for advanced undergraduate and early graduate students in pharmaceutical sciences or related fields.
Objective
The course will provide a solid overview of the science and issues in gene technology and genome science.
Content
1. Antibody phage technology The antibody molecule V genes, CDRs, basics of antibody engineering Principles of phage display Phagemid and phage vectors Antibody libraries Phage display selection methodologies Other phage libraries (peptides, globular proteins, enzymes) Alternative screening/selection methodologies DNA-encoded chemical libraries 2. Proteins: chemical modification and detection of biomolecular interactions Homo- and hetero-dimerization of proteins Chemical modifications of proteins Radioactive labeling of proteins Kinetic association and dissociation constants Affinity constant: definition and its experimental measurement 3. Genomics: Applications in Human Biology (whole book)
Resources
Lecture Notes
Skript "Antibody and Protein Engineering" by Prof. Dario Neri
Literature
Sandy B. Primrose and Richard M. Twyman Genomics: Applications in Human Biology Blackwell Publishing
General Information
- Language
- English
- Levels
- BSC , MSC
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- written 60 minutes
- Aids
- Keine
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Gentechnologie |
|
2 h weekly |