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Epigenetics
Last Updated: 2026-02-05 15:28:55
Abstract
Epigenetics studies mitotic and/or meiotic heritable traits that cannot be attributed to changes of the DNA sequence. The lecture will provide an overview over epigenetic phenomena and mechanisms. Furthermore, the impact of epigenetics on the development of different organisms will be discussed.
Objective
The aim of the course is to gain an understanding of epigenetic phenomena and mechanisms and their impact on development.
Content
-historical overview – concepts – genetics vs. epigenetics -chromatin – structure – locus- and function specific heterogeneity (transcription, silencing, heterochromatin) -epigenetic modifications of DNA (DNA methylation) and histones (acetylation, methylation, ubiquitination,…) -transmission of epigenetic modifications during cell divisions -stability/reversibility of epigenetic modifications -impact of epigenetics on development and environmental adaptation -epigenetic phenomena: • position effects • paramutation • genomic imprinting • X-inactivation and dosage compensation • RNAi • cosuppression • quelling • transvection • prions • meiotic silencing by unpaired DNA
General Information
- Language
- English
- Levels
- MSC
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- written 90 minutes
- Aids
- None
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture | Epigenetics |
|
2 h weekly |