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551-0342-00L 6 Credits BSC D-BIOL
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Systems Biology of Metabolism

Metabolic Networks

Lecturers: Prof. Dr. Uwe Sauer, Dr. Matthias Heinemann, Prof. Dr. Nicola Zamboni
Examiners: Prof. Dr. Nicola Zamboni
VVZ CR n/a

Last Updated: 2026-02-05 15:28:58

Abstract

Experimentally: quantitative physiology, bioreactor cultivation, mass spectrometry-based metabolomics, 13C-labeling experiments for metabolic flux analysis. Computationally: basics of the simulation software MatLab, stoichiometric models for simulation and analysis of network behavior. Soft skills to be trained: project planning, presentation, reporting, independent working style, team work.

Objective

Introduction to experimental and computational methods for the analysis of metabolic networks. Upon introduction of concepts, the course is mainly taught by project-oriented assignment of tasks that provide hands-on experience both in the wet-lab and the computation part.

Content

Experimentally: quantitative physiology, bioreactor cultivation, mass spectrometry-based metabolomics, 13C-labeling experiments for metabolic flux analysis. Computationally: basics of the simulation software MatLab, stoichiometric models for simulation and analysis of network behavior. Soft skills to be trained: project planning, presentation, reporting, independent working style, team work.

Resources

Literature

The course is not taught by a particular book, but some books are suggested for further reading: - Systems biology in Practice by Klipp, Herwig, Kowald, Wierling und Lehrach. Wiley-VCH 2005

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance
Es wird nur der hauptverantwortliche Examinator aufgeführt. Weitere Examinatoren: Die oben aufgeführten Dozierenden.

Course Components

Type Title Time & Place Hours
lecture with exercise Metabolic Networks
Permission from lecturers required for all students. Blockkurs im 1. Semesterviertel (beschränkt auf max. 10 Teilnehmende)
  • Tue 12:45-16:30 (HPT B 71)
  • Wed 07:45-16:30 (HPT B 71)
  • Thu 07:45-16:30 (HPT B 71)
  • Fri 07:45-16:30 (HPT B 71)
100 h semesterly

Offered In