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529-0133-00L 7 Credits DS , MSC D-CHAB , D-BIOL
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Bioinorganic Chemistry

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Last Updated: 2026-02-05 15:13:16

Abstract

Understanding of the role of metal ions in biological systems in relation to their function and their coordination. Reactivity and activation of small oxygen- and nitrogen-containing molecules, such as superoxide and nitrogen monoxide.

Objective

Understanding of the role of metal ions in biological systems in relation to their function and their coordination. Reactivity and activation of small oxygen- and nitrogen-containing molecules, such as superoxide and nitrogen monoxide.

Content

Significance of inorganic metal ions and small inorganic molecules in biochemical reactions (electron transport, catalysis, messenger function, modulation of the reactivity of biologically important radicals): Co: coenzyme B12; Mg and Mn: photosynthesis; O2: Haemoglobin, myoglobin, cytochrome P450, NO-synthase; defence against partial reduced oxygen species: superoxide dismutase and catalase; FeS, haem and Cu proteins: electron transport; Ni: urease and hydrogenase; Mo: electron transport and nitrogen fixation; Zn: carbonic anhydrase, zinc finger; Na and K: ion channels and pumps, Ca and Mg: calmodulin, ATP, DNA; Cr and Pt: toxicity.

Resources

Literature

Biological Inorganic Chemistry. Structure & Reactivity by Bertini, Gray, Stiefel and Valentine, 2007 University Science Books

General Information

Language
English
Levels
DS , MSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
oral 30 minutes

Course Components

Type Title Time & Place Hours
lecture with exercise Bioinorganic Chemistry
  • Wed 07:45-09:30 (HCI D 2)
  • Thu 08:45-09:30 (HCI D 2)
3 h weekly

Offered In