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251-0523-00L 5 Credits BSC , DS , MSC D-CHAB , D-PHYS , D-MAVT , D-INFK , D-ITET , D-MATH , D-BIOL , D-BSSE , D-HEST
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Computational Biology

This course is also taught at the University of Basle
VVZ CR n/a

Last Updated: 2026-02-05 15:14:53

Abstract

Study of computational techniques, algorithms and data structures used to solve problems in computational biology. Topics: basic biology, string alignment, phylogeny (distance, character, parsimony), molecular evolution, multiple sequence alignment, probabilistic and statistical models, Markov models, microarrays, dynamic programming, maximum likelihood and specialized DNA and protein analysis.

Content

This course lies in the intersection between Computer Science and Molecular Biology. The main purpose is to study computational techniques, algorithms and data structures which are usually applied to solve problems in Molecular Biology and Biochemistry. The following topics are likely to be covered: Introduction, mathematical models of evolution, protein and DNA sequence alignment and its meaning, phylogenetic tree construction, multiple sequence alignments, secondary structure prediction, molecular dynamics, threading, role of bioinformatics in drug design, etc. From the computer science point of view we concentrate our attention in practical solutions for the above problems. Biological knowledge is an asset but not a prerequisite.

General Information

Language
English
Levels
BSC , DS , MSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
oral 15 minutes

Course Components

Type Title Time & Place Hours
lecture Computational Biology
  • Thu 15:15-17:00 (CAB G 59)
2 h weekly
exercise Computational Biology
  • Thu 14:15-15:00 (CAB E 37)
1 h weekly

Offered In