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551-0348-00L 6 Credits BSC D-BIOL
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Signal Transduction: Principles and Quantitative Analysis

Lecturers: Dr. Ernesto Di Iorio, Dr. Marc Sohrmann, Prof. Dr. Attila Becskei
Examiners: Dr. Marc Sohrmann
VVZ CR n/a

Last Updated: 2026-02-05 15:18:47

Abstract

Analysis of the principles underlying signal transduction at the conceptual and molecular level, including development and solution of simple quantitative models.

Objective

The students will learn to analyze the general concepts and molecular mechanisms underlying signal transduction in different biological systems. They will be able to understand and develop simple quantitative models of chosen signaling pathways, and solve these models using Matlab.

Content

The course will be composed of two main components. First, starting with several well-known signaling pathways, we will identify some general concepts important for signal transduction, and discuss the relevant molecular mechanisms in the context of their biological function. Second, the students will be introduced to the transformation of signaling pathways into flowcharts and simple quantitative models, and the use of the standard software Matlab to numerically solve these models. The practical work will focus on a Matlab tutorial and computational analysis, and will be complemented by two small experiments carried out in the lab.

Resources

Literature

Documentation and recommended literature (review articles and selected primary literature) will be provided during the course.

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance
Es wird nur der hauptverantwortliche Examinator aufgeführt. Weitere Examinatoren: Die oben aufgeführten Dozierenden.

Course Components

Type Title Time & Place Hours
lecture with exercise Signal Transduction: Principles and Quantitative Analysis
Blockkurs im 2. Viertel des Sommersemesters Ort: HPM D7 (beschränkt auf max. 15 Teilnehmende)
No time listed 100 h semesterly

Offered In