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551-0346-00L 6 Credits BSC D-BIOL
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Study of the molecular mechanisms of learning and memory

Molecular Mechanism of Learning and Memory

Lecturers & Examiners: Prof. Dr. Isabelle Mansuy
VVZ CR n/a

Last Updated: 2026-02-05 15:18:47

Abstract

This course will provide an overview of molecular techniques used to investigate the mechanisms of learning and memory in the mouse. It will focus on state-of-the-art methods to manipulate gene expression in the adult brain, and analyse the effect in vitro using biochemical, molecular, electrophysiological and proteomic tools, and in vivo by behavioral testing.

Objective

The goal of this practical is to give students an overview of molecular techniques used to investigate the mechanisms of learning and memory in the mouse. It will focus on state-of-the-art methods to genetically manipulate gene expression in the adult brain, and analyse the effect in vitro using biochemical, molecular, electrophysiological and proteomic tools, and in vivo by behavioral testing.

Content

5-6 individual projects covering various aspects of the analysis of mouse models with impaired or improved learning and memory will be offered i.e. the analysis of transgene expression in various brain areas and cellular compartments, DNA chips in transgenic mice, phosphoproteomic analysis in neuronal subcompartments, examination of fear-associated memory in mutant mice.

Resources

Lecture Notes

Provided at the beginning of the practical.

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance

Course Components

Type Title Time & Place Hours
lecture with exercise Molecular Mechanism of Learning and Memory
Blockkurs im 2. Viertel des Sommersemesters Ort: Y55 H12, Uni-Irchel (beschränkt auf max. 12 Teilnehmende)
No time listed 100 h semesterly

Offered In