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535-0231-00L 2 Credits BSC D-CHAB
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Medicinal Chemistry and Biophysics II

Medizinische Chemie und Biophysik II

VVZ CR n/a

Last Updated: 2026-02-05 15:18:28

Abstract

The lectures in Medicinal Chemistry and Biophysics give an overview over the most important drug targets and the molecular mechanisms underlying the effects of therapeutic agents. Structure-function relationships, the biophysical rules underlying ligand-target interactions, as well as strategies for the development and optimization of pharmaceuticals will be discussed.

Objective

Understanding of the molecular mechanisms underlying the therapeutical and biological effects of modern drugs

Content

Molecular Mechanisms underlying the biological effects of synthetical and natural therapeutics. Structure-acitivity relationships, biophysical mechanisms underlying the interactions of ligands with their targets.

Resources

Lecture Notes

The slides presented in the course of the lecture and the pertaining learning goals will be sent to the students by e-mail the evening before the lecture

Literature

- H.J. Roth, H. Fenner, Arzneistoffe, Thieme Verlag Stuttgart (1994) - H.-D. Höltje, G. Folkers, Molecular Modelling, Verlag Chemie Weinheim (1996) - E. Mutschler, Arzneimittelwirkungen, Wiss. Verlagsges. Stuttgart (2001) - H.-J. Böhm, G. Klebe, H. Kubinyi, Wirkstoffdesign, Spektrum Akademischer Verlag, Heidelberg (1996) - D. Voit, J. Voit, Biochemie, Verlag Chemie Weinheim (1994) - PubMed

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
oral 20 minutes

Course Components

Type Title Time & Place Hours
lecture with exercise Medizinische Chemie und Biophysik II
  • Mon 09:45-11:30 (HIL E 8)
2 h weekly

Offered In