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535-0231-00L 2 Credits
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Medicinal Chemistry and Biophysics II

Medizinische Chemie und Biophysik II

Lecturers & Examiners: PD Dr. Vivianne Irene Otto, Dr. Christian Klein
VVZ CR n/a

Last Updated: 2026-02-05 15:09:47

Abstract

The lectures in Medicinal Chemistry and Biophysics give an overview over the most important drug targets and the molecular mechanisms of therapeutic drug effects, structure-function relationships, the biophysical rules underlying ligand-target interactions, as well as strategies for the development and optimization of pharmaceuticals.

Objective

Fähigkeit zur Beurteilung von Therapeutika hinsichtlich ihrer pharmazeutischen und molekularpharmakologischen Eigenschaften.

Content

Molekulare Wirkungsmechanismen synthetischer und natürlicher Therapeutika. Struktur-Wirkungsbeziehungen, biophysikalische Grundlagen der Ligand-Target Wechselwirkung.

Resources

Literature

- H.J. Roth, H. Fenner, Arzneistoffe, Thieme Verlag Stuttgart (1994) - H.-D. Höltje, G. Folkers, Molecular Modelling, Verlag Chemie Weinheim (1996) - E. Mutschler, Arzneimittelwirkungen, Wiss. Verlagsges. Stuttgart (2001) - H.-J. Böhm, G. Klebe, H. Kubinyi, Wirkstoffdesign, Spektrum Akademischer Verlag, Heidelberg (1996) - D. Voit, J. Voit, Biochemie, Verlag Chemie Weinheim (1994)

General Information

Language
German
Frequency
Yearly recurring

Examination

Type
session examination
Mode
oral 20 minutes

Course Components

Type Title Time & Place Hours
lecture with exercise Medizinische Chemie und Biophysik II
  • Mon 10:15-12:00 (HG D 7.1)
2 h weekly

Offered In