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551-1607-01L 1 Credits

Moelcular Biology and Biophysics III: Microanalytics and actual literatuere in protein chemistry

Mol'biol.u.Biophysik III: Mikroanalytik u. aktuelle Literatur in der Proteinchemie

Lecturers & Examiners: PD Dr. René Albert Brunisholz, Prof. em. Dr. Rudolf Glockshuber, Dr. Klaus Maskos, Prof. Dr. Eilika Weber-Ban
VVZ CR n/a

Last Updated: 2026-02-05 14:59:32

Abstract

Microanalytics of proteins and proteomes. Edman sequencing and chemical modification of proteins, modern proteome analytics, including MALDI-TOF and electrospray mass spectrometry, HPLC separation of peptides after proteolytic proteome digestion. Actual lieterature in protein chemistry.

Objective

Verständnis von Struktur/Funktionsbeziehungen in Proteinen, Proteinfaltung, Vertiefung der Kenntnisse in Biophysik, in physikalischen Messmethoden und modernen Methoden der Proteinreinigung und Protein-Mikroanalytik.

Content

Thermodynamik und Kinetik der Proteinfaltung Spektroskopische Methoden zur Charaktersierung von Proteinen Prionen und Amyloide Molekulare Chaperone Prinzipien der enzymatishen Katalyse Katalytische RNA und RNAi Biophysik von biologischen Membranen Struktur von Membranproteinen Moderne Proteomanalytik

Resources

Lecture Notes

seehttp://www.mol.biol.ethz.ch/teaching

Literature

- Creighton, T.E., Proteins, Freeman, (1993) - Fersht, A., Enzyme, Structure and Mechanism in Protein Science (1999), Freeman - Berg, Tymoczko, Stryer: Biochemistry (5th edition), Freeman (2001)

General Information

Language
German
Frequency
Yearly recurring

Examination

Type
session examination
Mode
oral 30 minutes

Course Components

Type Title Time & Place Hours
lecture with exercise Mol'biol.u.Biophysik III: Mikroanalytik u. aktuelle Literatur in der Proteinchemie
  • Mon 10:45-11:30 (HCI J 6)
1 h weekly

Offered In