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535-0240-00L 2 Credits
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Praktikum Biopharmazie

Beginn am 23.5.2005
VVZ CR n/a

Last Updated: 2026-02-05 15:02:26

Abstract

Consolidation and implementation of Biopharmacy I. Experimental determination of pharmacokinetic parameters in vitro: biotransformation experiments (phase I and II) with rat liver microsomes; determination of partition coefficients in the octanol/buffer system including stability testing; protein binding and displacement studies with bovine serum albumin as binding partner.

Objective

Consolidation and implementation of Biopharmacy I (50-241 und 50-242).

Content

Experimental determination of pharmacokinetic parameters in vitro: biotransformation experiments (phase I and II) with rat liver microsomes; determination of partition coeffi-cients in the octanol/buffer system including stability testing; protein binding and dis-placement studies with bovine serum albumin as binding partner.

Resources

Lecture Notes

Biopharmazie Praktikumsskript (Krämer/Wunderli-Allenspach)

Literature

P. Langguth, G. Fricker, H. Wunderli-Allenspach "Biopharmazie", Wiley-VCH Verlag, Weinheim, 2004

General Information

Language
German
Frequency
Yearly recurring

Examination

Type
ungraded semester performance

Course Components

Type Title Time & Place Hours
practical/laboratory course Praktikum Biopharmazie
Permission from lecturers required for all students.
  • 29.03. - 01.07 Date 12:45-16:30 (HCI E 476.1)
45 h semesterly

Offered In