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Abstract
This course develops a rigorous, broad, and hands on understanding of how electromagnetic fields interact with neural systems across scales, from ion channels and single axons to networks and whole brain models, with a focus on the underlying biophysics and corresponding modeling approaches.
Objective
Students learn the computational foundations of simulations and gain experience coupling EM exposure simulations with biophysical neuron and network models to predict activation, selectivity, and safety. Clinical guest lectures connect models to applications in bioelectronic medicine (e.g., vagus nerve stimulation for cardiovascular regulation after heart transplantation, spinal cord stimulation for the restoration of locomotion in paraplegics) and non invasive brain stimulation (e.g., to improve learning), while dedicated sessions cover neural recording methods, personalized precision medicine, optimization, and verification/validation/uncertainty-quantification for regulatory grade in silico evidence.