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Abstract
The course offers an introduction into the molecular biology of fungi by participation in a current research project on Molecular Defense Mechanisms of Fungi. The performed experiments, in conjunction with accompanying seminars enables the students to answer questions regarding central aspects of innate defense mechanisms and the life style of multicellular fungi.
Objective
The course enables the students to answer questions regarding central aspects of innate defense mechanisms and the life style of multicellular fungi, and their experimental accessibility.
Content
Experiments include the isolation, identification and characterization of defense effector molecules from multicellular fungi. Methods include molecular genetics, biochemistry, mass spectrometry and biotoxicity assays towards different model organisms including fungi, bacteria, insects and nematodes. Experiments are supported by seminars giving an overview over Fungal Defense Mechanisms and Fungal Lifestyle.
Resources
Literature
http://www.micro.biol.ethz.ch/research/aebi/kuenzler/publications