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Natural Product Synthesis
Naturstoffsynthese
Last Updated: 2026-02-05 14:55:03
Abstract
After an introductory overview on secondary metabolites the terms synthetic strategy and tactics will be illustrated. In addition, reaction mechanisms and aspects of dynamic stereochemistry will be discussed.
Objective
To get to know some important retrosynthetic concepts. Increase and improve the knowledge concerning synthetically important reactions, their mechanisms and stereochemical implications.
Content
1.1. General aspects of natural products and secondary metabolites 1.2. Biogenetic pathways towards secondary metabolites 2. Mannich-reaction and iminiumion-cyclisations as key strategies in alkaloid synthesis 3. Cycloadditions and electrocyclic reaction as synthetic strategies 4. Biomimetic strategies 5. Tandem reactions as key steps in natural product synthesis
Resources
Lecture Notes
Single sheets corresponding with the shown and discussed overheads will be handed out. The exercises are handed out one after the other, sheets with the proposed solutions at the appropriate time.
Literature
No specific book is required. A standard textbook on Organic Chemistry, like Streitwieser, Vollhard, Morrison-Boyd and so on may be helpful. For students with an above-average interest in the subject, the books cited above in the German version offer additional intellectual stimulus.
General Information
- Language
- German
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- written 60 minutes
- Aids
- Keine.
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Naturstoffsynthese |
|
3 h weekly |