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551-1129-00L 6 Credits BSC D-BIOL , D-CHAB

Understanding and Engineering Microbial Metabolism

Lecturers & Examiners: Prof. Dr. Julia Vorholt-Zambelli
Number of participants limited to 6. The enrolment is done by the D-BIOL study administration.
VVZ CR n/a

Last Updated: 2026-06-03 00:07:29

Abstract

The focus of this laboratory course is on current research topics related to metabolic engineering and the general understanding of metabolism, particularly in relation to one carbon metabolism. Projects will be carried out in small teams.

Objective

The course aims at introducing technologies to investigate bacterial metabolism and key principles of metabolic engineering. The main focus of this block course is on practical work and will familiarize participants with complementary approaches, in particular genetic, biochemical and analytical techniques including metabolomics. Results will be presented by students in scientific presentations. Another goal is to learn how to write a scientific report.

Content

The course and will include topics such as pathway elucidation & engineering and related ongoing research projects in the lab. Experimental work applied during the course will comprise methods such as cloning work & transformation, growth determination, enzyme activity assays, liquid-chromatography mass-spectrometry and dynamic labeling experiments.

Resources

Lecture Notes

None

Literature

Will be provided at the beginning of the course.

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance
Student evaluations will be based on a project presentation and a written report.Details will be communicated at the beginning of the course.Students are obliged to be present throughout the block course.Cancellation: If you have to deregister from a course that has been assigned to you (just emergency reasons), please notify in written the course coordinator at least four weeks before the course starts, for courses in the 1st quarter, a cancellation period of one week applies. The study secretariat D-BIOL must also be informed (email CC [email protected]) so that the enrollment is deleted. Otherwise the course is considered as "failed".

Course Components

Type Title Time & Place Hours
practical/laboratory course Understanding and Engineering Microbial Metabolism
Permission from lecturers required for all students. Block course in the 1st quarter of the autumn semester.
No time listed 100 h semesterly

Offered In