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Organic Chemistry III: Introduction to Asymmetric Synthesis
Last Updated: 2026-06-03 00:07:29
Abstract
Methods of Asymmetric Synthesis
Objective
Understanding of the basic principles of diastereoselective synthesis
Content
Conformational analysis: acyclic and cyclic systems; Diastereoselective sigmatropic rearrangements; Diastereoselective Carbonyl addition reactions: Cram- and Felkin-Anh models, carbonyl Lewis acid interactions, chelate controlled reactions; chemistry of enolates, selective formation; asymmetic enolate alkylation; aldol reactions, allyl- and crotyl-metal chemistry; cyclisations, Baldwin rules; Diastereoselective olefin functionalization: hydroboration, dihydroxylation, epoxidation.
Resources
Literature
E. M. Carreira and L. Kvaerno Classics in Stereoselective Synthesis, Wiley-VCH 2009 Evans' Problems in Organic Chemistry App
General Information
- Language
- English
- Levels
- BSC , MSC
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- written 60 minutes, oral 30 minutes
- Aids
- Keine
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Organic Chemistry III: Introduction to Asymmetric Synthesis | No time listed | 3 h weekly |