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262-0202-00L 4 Credits DR , MSC D-BSSE , D-INFK

Quantitative Genetics and Genomics

Lecturers & Examiners: Prof. Dr. Na Cai
VVZ CR n/a

Last Updated: 2026-06-03 00:14:08

Abstract

This course introduces students to computational and statistical approaches for preprocessing, analyzing and interpreting genetic datasets in the context of human health and disease.

Objective

Students get a good theoretical foundation and practical confidence in: 1. Bioinformatics tools for sequencing and genotyping data preprocessing and quality control 2. Assessment of genetic architecture of complex phenotypes 3. Association tests 4. Phenotype prediction

Content

Mix of lectures and code-/presentation-based exercise sessions 1. 2 weeks on sequence bioinformatics 2. 2 weeks on structure in genetic data 3. 5 weeks on genetic architecture 4. 2 weeks on predictions and inferences 5. 2 weeks on genome to function

Resources

Lecture Notes

Lecture slides will be made available through Moodle a week in advance of each lecture

Literature

The reading list will be made available at the beginning of the course. Papers to be read during the journal club sessions (part of the exercises) will be made available through Moodle a week in advance of the respective exercis esession (students will be notified during exercise session in the week before).

General Information

Language
English
Levels
DR , MSC
Frequency
Yearly recurring

Examination

Type
end-of-semester examination
Mode
written 120 minutes
Aids
None
The examination counts for 80% of the final gradeA journal club (teamwork) counts for 20% of the final grade

Registration & Places

Max Places
50

Course Components

Type Title Time & Place Hours
lecture with exercise Quantitative Genetics and Genomics
The course takes place in classroom in BASEL. Atteniont: the lecture will not take place on 25 February (Fasnacht in Basel).
  • Wed 11:15-14:00 (BSS E 23)
3 h weekly

Offered In