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P&S: Clinical Genomics
Last Updated: 2026-06-03 00:14:20
Abstract
The category of "Laboratory Courses, Projects, Seminars" includes courses and laboratories in various formats designed to impart practical knowledge and skills. Moreover, these classes encourage independent experimentation and design, allow for explorative learning and teach the methodology of project work.
Objective
Bioinformatics and the computational analysis of next-generation sequencing data are the foundation of many medical discoveries, personalized medicine, high throughput diagnostic techniques, and the early detection of cancer and autoimmune diseases. A dedicated machine (called a sequencer) extracts lots of random fragments of a DNA sequence, known as reads. Small, handheld sequencers such as ONT MinION and Flongle make it possible to sequence bacterial and viral genomes on-site. This enables disease outbreak analyses (i.e., for COVID-19 or Ebola) and the on-site analysis of patient samples. A prominent example is the study of the human microbiome in liquid biopsy samples (i.e., blood samples). The microbiome is strongly related to human health and allows for the early diagnosis of diseases like Parkinson's, Alzheimer's, and cancer. In this course, we will cover the basics of genome analysis for medical applications, high-throughput diagnostics, and the early detection and prevention of diseases. Students will experimentally evaluate different algorithms and machine-learning techniques to uncover somatic mutations in cancer and develop tools dedicated to microbiome discovery and high-throughput disease diagnostics. The course is conducted in English. Arvid Gollwitzer is the main supervisor for this course. Please contact him if you are interested in taking this course: [email protected]
Content
Course website: Link
General Information
- Language
- English
- Levels
- BSC
- Frequency
- Semesterly recurring
Examination
- Type
- ungraded semester performance
Registration & Places
- Signup Start
- 13.02.2026
- Signup End
- 27.02.2026
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| practical/laboratory course |
P&S: Clinical Genomics
Does not take place this semester.
Für den Zugang zum Angebot und zur Einschreibung loggen Sie sich hier ein (mit Ihrem n.ETHZ account):
Bitte beachten Sie, dass die Seite jeweils erst zwei Wochen vor Semesterbeginn zugänglich ist und im Verlauf des Semesters wieder abgeschaltet wird. Die Einschreibung ist nur von Freitag vor Semesterbeginn bis zum ersten Freitagmittag im Semester möglich.
To access the offer and to enroll for courses log in (with your n.ethz account):
Please note that the P&S-site is accessible no earlier than two weeks before the start of the semester until four weeks after the start of the semester. Enrollment is only possible from Friday before the start of the semester until noon of the first Friday in the semester.
|
No time listed | 4 h weekly |
Offered In
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Laboratory Courses, Projects, Seminars (A minimum of 15 cp must be achieved in the category "Laboratory Courses, Projects, Seminars")
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Projects & Seminars (only for BSc EEIT) (Enrolment is only possible for students in the BSc Electrical Engineering and Information Technology, from Friday before the start of the semester. Places are allocated using the P&S application tool ( ). For more offers, see "Projects & Seminars (open to all)".)
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