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535-0231-00L 2 Credits BSC , MSC D-HEST , D-BIOL , D-CHAB

Medicinal Chemistry II

Medizinische Chemie II

Lecturers & Examiners: Prof. Dr. Jonathan Hall, Prof. Dr. Amy E. Fraley
VVZ CR n/a

Last Updated: 2026-06-03 00:14:04

Abstract

The lectures give an overview of selected drugs and the molecular mechanisms underlying their therapeutic effects in disease. The historical and modern-day methods by which these drugs were discovered and developed are described. Structure-function relationships and the biophysical rules underlying ligand-target interactions will be discussed and illustrated with examples.

Objective

Basic understanding of therapeutic agents with respect to molecular, pharmacological and pharmaceutical properties.

Content

Molecular mechanisms of action of drugs. Structure function and biophysical basis of ligand-target interactions.

Resources

Lecture Notes

Will be provided electronically in parts before each individual lecture.

Literature

- G.L. Patrick, "An Introduction to Medicinal Chemistry", 5th edition, Oxford University Press (2013) - D. Steinhilber, M. Schubert-Zsilavecz, H.J. Roth, "Medizinische Chemie", Deutscher Apotheker Verlag Stuttgart (2005) - J.H. Block, J.M. Beale, "Organic Medicinal and Pharmaceutical Chemistry", 11th edition, Lippincott, Williams, Wilkins (2002) - A. Gringauz, "How Drugs Act and Why", Wiley (1997) - R. Silverman and M. Holladay, "The Organic Chemistry of Drug Design and Drug Action" 3rd Edition, Academic Press, (2014)

General Information

Language
English
Levels
BSC , MSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 120 minutes
Aids
None

Course Components

Type Title Time & Place Hours
lecture Medizinische Chemie II
  • Mon 09:45-11:30 (HCI J 3)
2 h weekly

Offered In