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636-0109-00L 4 Credits DR , MSC D-BSSE , D-INFK , D-GESS
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Stem Cells: Biology and Therapeutic Manipulation

Lecturers & Examiners: Prof. Dr. Timm Schroeder
VVZ CR n/a

Last Updated: 2026-06-01 11:30:44

Abstract

Stem cells are central in tissue regeneration and repair, and hold great potential for therapy. We will discuss the role of stem cells in health and disease, and possibilities to manipulate their behavior for therapeutic application. Basic molecular and cell biology, engineering and novel technologies relevant for stem cell research and therapy will be discussed.

Objective

Understanding of current knowledge, and lack thereof, in stem cell biology, regenerative medicine and required technologies. Theoretical preparation for practical laboratory experimentation with stem cells.

Content

We will use different diseases to discuss how to potentially model, diagnose or heal them by stem cell based therapies. This will be used as a guiding framework to discuss relevant concepts and technologies in cell and molecular biology, engineering, imaging, bioinformatics, tissue engineering, that are required to manipulate stem cells for therapeutic application. Topics will include: - Embryonic and adult stem cells and their niches - Induced stem cells by directed reprogramming - Relevant basic cell biology and developmental biology - Relevant molecular biology - Cell culture systems - Cell fates and their molecular control by transcription factors and signalling pathways - Cell reprogramming - Disease modelling - Tissue engineering - Bioimaging, Bioinformatics - Single cell technologies

General Information

Language
English
Levels
DR , MSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 120 minutes
Aids
none allowed
Presentation (individually or in teams) of literature research about a relevant topic (list of possible topics provided at the first lecture) is a is a compulsory continuous performance assessment of this course. It will be graded as pass/fail, and is required to enroll for the examination and to pass this course.

Course Components

Type Title Time & Place Hours
lecture with exercise Stem Cells: Biology and Therapeutic Manipulation
The lecture takes place in classroom in BASEL. Attention: the lecture starts in the second week of the semester.
  • Wed 16:15-19:00 (BSS E 21)
3 h weekly

Offered In