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Genomic Animal Breeding
Last Updated: 2026-06-01 11:32:50
Abstract
Molecular marker-based methods and applications in animal breeding and genetics are introduced by discussing approaches to discover genomic regions associated with monogenic and complex traits, genomic prediction as well as the properties of genomic breeding values. Participants analyse real genomic data with the R-package and thus acquire the skills to carry out own research projects.
Objective
After the course, students will be able to - work with widely-used formats of genomic data - process and interpret raw sequencing and genotyping data - explain and identify the challenges, opportunities and risks associated with applying molecular marker data in animal breeding and animal genetics - apply common statistical methods to correlate phenotypes and genotypes - carry out research projects that involve molecular marker data
Content
- Principles of generating, processing and analysing whole-genome sequencing and genotyping data - Statistical approaches to map quantitative trait loci using genome-wide association studies - Calculation of genomic relationship and inbreeding coefficients - Principles of genomic prediction and selection - Bioinformatics approaches to characterize sequence variation at nucleotide level - Approaches to identify causal mutations underlying Mendelian traits - Strategies to consider Mendelian traits in genomic breeding programs
Resources
Lecture Notes
The slides will be provided in advance of each lecture.
Learning Materials (Links)
- Additional links
- Mapping genes for complex traits in domestic animals and their use in breeding programmes
- Prediction of total genetic value using genome-wide dense marker maps
- Highly effective SNP-based association mapping and management of recessive defects in livestock
- Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle
- Harmful recessive effects on fertility detected by absence of homozygous haplotypes
- A nonsense mutation in TMEM95 causes idiopathic male subfertility in cattle
General Information
- Language
- English
- Levels
- MSC
- Frequency
- Yearly recurring
Examination
- Type
- graded semester performance
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Genomic Animal Breeding |
|
3 h weekly |