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Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences)
Praktikum Organische Chemie (für Biol./Pharm.Wiss.)
Last Updated: 2026-02-05 16:30:54
Abstract
Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography)Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
Objective
Learn the basic techniques for the preparation and purification of organic compounds. Learn to take accurate notes of the experiments and to write reports. Deepen the understanding of reaction mechanisms.
Content
Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography). Synthetic part (main part): at least 8 synthesis steps (one- to two-step preparations) from the following classes of reactions: 1. nucleophilic substitution at C(sp3), 2. elimination or electrophilic addition to a C=C bond, 3. electrophilic aromatic substitution, 4. reduction of an aldehyde/ketone, 5. Grignard reaction, 6. heterocyclization with imine/enamine formation, 7. synthesis of a carboxylic acid derivative by acyl group transfer, 8. aldol, Claisen, Mannich, Michael reaction or Robinson anellation. Introduction to database searches (Reaxys, SciFinder).
Resources
Lecture Notes
Written documents are distributed via Moodle course.
Literature
1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden); Birkhäuser Verlag; Basel; 1990. 2) J. Leonard, B. Lygo, G. Procter; Advanced Practical Organic Chemistry; CRC Press Taylor & Francis Group; Boca Raton, FL; 2013.
General Information
- Language
- German
- Levels
- BSC
- Frequency
- Yearly recurring
Examination
- Type
- ungraded semester performance
Registration & Places
- Signup End
- 06.09.2024
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| practical/laboratory course |
Praktikum Organische Chemie (für Biol./Pharm.Wiss.)
Permission from lecturers required for all students.
Vorbesprechungstermin und weitere Informationen werden im Moodle-Kurs bekanntgegeben. Arbeitsbeginn jeweils zur vollen Stunde (s.t.).
Further information such as date, time, and place of the introductory lecture: see Moodle course. The lab always starts at the top of the hour (s.t.).
|
|
12 h weekly |