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Structure Elucidation by NMR
Last Updated: 2026-02-05 16:37:50
Abstract
Structure Elucidation of Complex Organic Molecules by NMR
Objective
Structure elucidation of complex organic molecules (including peptides, oligosaccharides and oligonucleotides) by advanced 1D and 2D NMR spectroscopy: Finding the constitution, rel. configuration and the conformation of an unkown molecule. The emphasis of the course is on the selection of optimal strategies for the solution of a given problem. Discussing and solving these problems by the combined application of various 2D methods form an important part of the course. This also includes the use of state-of-the-art methods for computer assisted structure elucdation (CASE) and chemical shift prediction.
Content
Important experiments for structure elucidation. Finding the optimal strategy for a given problem. Spectral processing for optimal results. Spectral interpretation. Assignment strategies for complex molecules. Common Artefacts. Computer assisted structure elucidation incl. introduction to relevant software and hands-on application. Chemical shift prediction. Discussion of challenging problem sets during class.
Resources
Lecture Notes
Scripts (in English) are distributed in the course
Literature
"T.D.W. Claridge, High Resolution NMR Techniques in Organic Chemistryî, Pergamon Press, 1999. (NMR Teil) Further reading and citations are listed in the script.
General Information
- Language
- English
- Levels
- BSC , DR , MSC
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- written 60 minutes
- Aids
- Alle, ausser Telekommunikation und Computer, Taschenrechner erlaubt
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Structure Elucidation by NMR |
|
2 h weekly |
Offered In
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Electives (Students are free to choose from a range of D-CHAB chemistry courses appropriate to their level of study (please note admission requirements). In case of doubt, contact the student administration.)
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Electives (Students are free to choose from a range of D-CHAB chemistry courses appropriate to their level of study (please note admission requirements). In case of doubt, contact the student administration.)
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Doctorate Chemistry and Applied Biosciences (For further information: )
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