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Bone Biology and Consequences for Human Health
Last Updated: 2026-02-05 16:37:56
Abstract
Bone is a complex tissue that continuously adapts to mechanical and metabolic demands. Failure of this remodeling results in reduced mechanic stability ot the skeleton. This course will provide the basic knowledge to understand the biology and pathophysiology of bone necessary for engineering of bone tissue and design of implants.
Objective
After completing this course, students will be able to understand: a) the biological and mechanical aspects of normal bone remodeling b) pathological changes and their consequences for the musculoskeletal system c) the consequences for implant design, tissue engineering and treatment interventions.
Content
Bone adapts continuously to mechanical and metabolic demands by complex remodeling processes. This course will deal with biological processes in bone tissue from cell to tissue level. This lecture will cover mechanisms of bone building (anabolic side), bone resorption (catabolic side), their coupling, and regulation mechanisms. It will also cover pathological changes and typical diseases like osteoporosis. Consequences for musculoskeletal health and their clinical relevance will be discussed. Requirements for tissue engineering as well as implant modification will be presented. Actual examples from research and development will be utilized for illustration.
General Information
- Language
- English
- Levels
- BSC , MSC , NDS
- Frequency
- Yearly recurring
Examination
- Type
- graded semester performance
- Digital
- The exam takes place on devices provided by ETH Zurich.
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture |
Bone Biology and Consequences for Human Health
Does not take place this semester.
This course unit will take place in autumn semester from 2024 onwards.
|
No time listed | 2 h weekly |
Offered In
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Bioengineering (The courses listed in this category “Core Courses” are recommended. Alternative courses can be chosen in agreement with the tutor.)
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Biomedical Engineering Master (Only courses offered under "GESS Science in Perspective" count in this category. See "Offered in" tab in course view. For more information, please refer to )
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Recommended Elective Courses (These courses are particularly recommended for the Biomechanics track. Please consult your track adviser if you wish to select other subjects.)
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