Galenical Pharmacy I+II

Abstract

Principles and technologies for the manufacturing of dosage forms and drug delivery systems. Knowledge of pharmaceutical excipients, materials, containers, liquid, solid and semi-solid dosage forms, their production, function, quality and application.

Objective

Knowledge of the most important pharmaceutical excipients, materials, containers, liquid, solid and semi-solid dosage forms, of their production, function, quality, stability and application. Comprehension of the molecular interactions in solid state, solution and colloidal systems.

Content

Introduction and overview of important fundamentals, principles and technologies for the development and manufacturing of dosage forms and drug delivery systems. Overview of the most important pharmaceutical excipients and polymers, their structure, properties and processing; importance of materials properties for containers. Pharmaceutical solvents, fundamentals of solubility and solubilization of drugs. Water treatment processes, sterilization techniques and quality requirements of pharmaceutical water. Parenteral dosage forms and liquid ophthalmics. Surfactants, micelle formation and colloidal systems. Liquid suspensions and emulsions. Stabilization measures in dosage forms. Important fundamentals, principles and technologies for the development and manufacturing of solid dosage forms and drug delivery systems. Powder technology. Tablets and tabletting. Coating technologies. Drug dissolution and release. Hard and soft gelatin capsules. Introduction to drug delivery and targeting. Drug delivery systems for peroral, transdermal, parenteral and mucosal administration.

Resources