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535-0041-00L 2 Credits MSC , WBZ D-CHAB

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Pharmacology and Toxicology III

Lecturers & Examiners: Prof. Dr. Michael Arand, Prof. Dr. Ursula Quitterer, Prof. Dr. Yohei Yamauchi

VVZ CR n/a

Last Updated: 2026-02-05 16:14:56

Abstract

The course is divided into two parts. The first part provides a detailed understanding of drugs and the pharmacotherapy of infectious diseases and cancer. The second part gives an overview of the field of pharmacogenomics and toxicogenomics with a special focus on the role of genetic polymorphisms in disease susceptibility, drug response and adverse effects.

Objective

The course advances basic knowledge in pharmacology and toxicology. Special emphasis is placed on the interrelationship between pharmacological, pathophysiological and clinical aspects of drug therapy in the fields of infectious diseases and cancer. The course also provides an overview of the field of pharmacogenomics and toxicogenomics, with a special focus on the role of genetic polymorphisms in disease susceptibility, drug response and adverse effects.

Content

Topics include the pharmacology and pharmacotherapy of infectious diseases and cancer. In the field of pharmacogenomics and toxicogenomics, the course is focused on genetics, genome-wide association studies, examples of genetic variability of drug metabolism and drug responses, and the relevance of pharmacogenomics and toxicogenomcis for clinical drug development.

Resources

Lecture Notes

A script is provided for each lecture. The scripts define important and exam-relevant contents of the lectures. Scripts do not replace the lectures.

Literature

Recommended reading: The classic textbook in Pharmacology: Goodman and Gilman`s The Pharmacological Basis of Therapeutics Laurence Brunton, Bjorn C. Knollman. 14th edition (2022) ISBN-10: 1264258070 ISBN-13: 978-1264258079 or Klaus Aktories, Veit Flockerzi, Ulrich Förstermann, Franz Hofmann. Allgemeine und spezielle Pharmakologie und Toxikologie. 13th edition (2022) Urban & Fischer (Elsevier) ISBN-13: 978-3-437-42622-3

General Information

Language: English
Levels: MSC , WBZ
Frequency: Yearly recurring

Examination

Type: session examination
Mode: written 60 minutes
Aids: None

In frame of the lecture course each student has to prepare and give a 5-minute oral presentation on a topic of pharmacology and toxicology III. The list of topics is provided during the first lecture. The oral presentation (and the electronic PDF-File of the presentation) is graded as passed or failed. The successful presentation improves the grade of the final session exam by 0.25.

Course Components

Type	Title	Time & Place	Hours
lecture with exercise	Pharmacology and Toxicology III	Mon 13:45-15:30 (HCI G 3)	2 h weekly