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Practical Course Organic Chemistry (for Students of Biology and Pharmaceutical Sciences)
Praktikum Organische Chemie (für Biol./Pharm.Wiss.)
Last Updated: 2026-02-05 16:16:01
Abstract
Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography)Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses).
Objective
Learn the basic techniques for the preparation and purification of organic compounds. Learn to take accurate notes of the experiments and to write reports. Deepen the understanding of reaction mechanisms.
Content
Analytical part: basic operations for the separation of mixtures of organic compounds (recrystallization, distillation, extraction, chromatography). Synthetic part (main part): at least 8 synthetic steps (one- or two-step syntheses) from the following classes of reactions: 1. nucleophilic substitution at C(sp3), 2. elimination or electrophilic addition to C=C, 3. electrophilic aromatic substitution, 4. oxidation, 5. reduction, 6. Grignard reaction, 7. synthesis of a carboxylic acid derivative, 8. Aldol-, Claisen-, Mannich-, Michael reaction or Robinson annulation. Introduction to database searches (Reaxys, SciFinder).
Resources
Lecture Notes
Documentation will be handed out at the beginning of the course.
Literature
1) P. Wörfel, M. Bitzer, U. Claus, H. Felber, M. Hübel, B. Vollenweider, Laborpraxis (Bd. 1: Einführung, allgemeine Methoden; Bd. 2: Messmethoden; Bd. 3: Trennungsmethoden; Bd. 4: Analytische Methoden); Birkhäuser Verlag; Basel; 1990. 2) J. Leonard, B. Lygo, G. Procter; Advanced Practical Organic Chemistry; CRC Press Taylor & Francis Group; Boca Raton, FL; 2013.
General Information
- Language
- German
- Levels
- BSC
- Frequency
- Yearly recurring
Examination
- Type
- ungraded semester performance
Registration & Places
- Signup End
- 08.09.2023
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| practical/laboratory course |
Praktikum Organische Chemie (für Biol./Pharm.Wiss.)
Permission from lecturers required for all students.
Vorbesprechungstermin und weitere Informationen werden im Moodle-Kurs bekanntgegeben. Arbeitsbeginn jeweils zur vollen Stunde (s.t.).
Further information such as date, time, and place of the introductory lecture: see Moodle course. The lab always starts at the top of the hour (s.t.).
|
|
12 h weekly |