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529-0221-00L 3 Credits BSC D-CHAB
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Organic Chemistry I

Organische Chemie I

Lecturers & Examiners: Prof. Dr. Helma Wennemers
VVZ CR n/a

Last Updated: 2026-02-05 16:15:17

Abstract

This course will build upon the basic knowledge of structure and reactivity of organic molecules gained in AC/OCI and AC/OCII. The module aims to provide a wide understanding of the occurrence, synthesis, properties, and reactivity of carbonyl compounds.

Objective

The goal of this course is the acquisition of a basic repertoire of synthetic methods including important reactions of aldehydes, ketones, carboxylic acids, and carboxylic acid derivatives. Particular emphasis is placed on the understanding of reaction mechanisms and the correlation between structure and reactivity. A deeper understanding of the concepts presented during the lecture is reached by solving the problems handed out each time and discussed one week later in the exercise class.

Content

Structure and properties of carbonyl compounds. Chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds). Synthesis and reactivity of carboxylic acid derivatives (nucleophilic addition-elimination reactions). Oxidations and reductions. Reactivity at the alpha-carbon (keto/enol tautomerization, alpha-functionalization, aldol reactions, conjugate addition reactions). Introduction to the concepts of protecting groups and retrosynthesis.

Resources

Lecture Notes

The lecture slides, problem sets, and additional documents are provided online. Link:https://wennemers.ethz.ch/education.html

Literature

Clayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012. Additional literature will be provided at the beginning of the class and in the lecture notes.

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 60 minutes
Aids
keine

Course Components

Type Title Time & Place Hours
lecture Organische Chemie I
  • Wed 11:45-13:30 (HPV G 4)
2 h weekly
exercise Organische Chemie I
Groups are selected in myStudies. Die Übungen beginnen in der zweiten Semesterwoche.
  • Mon 11:45-12:30 (HCI D 6)
  • Mon 11:45-12:30 (HCI E 8)
  • Mon 11:45-12:30 (HCI H 2.1)
  • Mon 11:45-12:30 (HCI J 8)
  • Tue 07:45-08:30 (HCI E 2)
  • Tue 07:45-08:30 (HCI E 8)
  • Tue 07:45-08:30 (HCI F 8)
  • Tue 07:45-08:30 (HCI J 3)
  • Tue 07:45-08:30 (HCI J 8)
1 h weekly

Offered In