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Precision Medicine
Last Updated: 2026-02-05 16:01:57
Abstract
Precision Medicine is a new approach in health care aiming to deliver personalised prevention and treatment for human diseases by considering individual differences in lifestyle, environment, and biology. As Precision Medicine is a multidisciplinary approach, the content of this course includes topics in genetics, epigenetics, pharmacogenetics.
Objective
The course enables participants to... 1. describe the difference between traditional and precision medicine, the goal of precision medicine, and of different patterns of inheritance. 2. recall genetic definitions and genetic variants, and explain how to study genetic variants. 3. explain different next generation sequencing (NGS) technologies and standard NGS data analysis workflow for Mendelian diseases. 4. demonstrate steps involved in variant analysis and interpretation, and how to use public repositories to interpret variants of interest. 5. explain different types of omics data. 6. describe the difference between screening and diagnostic genetic tests 7. describe how to identify patients who might be candidates for whole genome sequencing. 8. report on risks, benefits and limit actions of genomic testing in individuals interested in learning about their future risks, and report on positive, negative, uncertain and unexpected whole genome test results in collaboration with genetic specialists. 9. communicate risks, benefits, and limitations of whole genome sequencing, interpret the results from testing. 10. describe examples of complicated ethical or clinical situations in personalised medicine, name ethical issues that arise, and identify behaviors to deal with ethical issues. 11. describe variability in drug response and examples of drug therapy and adverse drug reactions, explain how to interpret the pharmacogenomic test results, explain what pharmacogenomic tests are available if a patient is a candidate for pharmacogenomic testing. 12. explain analytic and clinical validity of pharmacogenomic tests, describe adverse drug reactions and the mechanisms underlying the variability in drug response. 13. show how to handle biological samples, use the laboratory equipment and infrastructure, explain how to genotype biological samples for a genetic disease, and how to evaluate and communicate results.
General Information
- Language
- English
- Levels
- NDS , WBZ
- Frequency
- Yearly recurring
Examination
- Type
- ungraded semester performance
Registration & Places
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Precision Medicine | No time listed | 42 h semesterly |