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551-1415-00L 6 Credits BSC D-CHAB , D-BIOL
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Image-Based Drug Screening in Human Blood for Personalized Medicine

Lecturers & Examiners: Dr. Berend Snijder
Number of participants limited to 5. The enrolment is done by the D-BIOL study administration.
VVZ CR n/a

Last Updated: 2026-02-05 16:01:23

Abstract

Image based screening allows to measure in high throughput the phenotype of millions of individual cells to external perturbations. We have recently shown that image-based screening in human blood can help to find active treatments for patients with blood cancers. In this course we will take the students through the entire workflow (to the extent that biosafety regulations allow it).

Objective

Take the students through the entire workflow from experimental design, to screen, to imaging and analysis. -Learn to design an image-based screening experiment -Observe human blood sample handling -Perform immunofluorescence & automated confocal microscopy -Image analysis and result interpretation -Result presentation

Resources

Literature

-Relevant study: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026 (17)30208-9/fulltext -Editorial commentary: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026 (17)30213-2/fulltext

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance
Students are obliged to be present throughout the block course.Cancellation: If you have to deregister from a course that has been assigned to you (just emergency reasons), please notify in written the course coordinator at least four weeks before the course starts, for courses in the 1st quarter, a cancellation period of one week applies. The study secretariat D-BIOL must also be informed (email CC [email protected]) so that the enrollment is deleted. Otherwise the course is considered as "failed".

Course Components

Type Title Time & Place Hours
practical/laboratory course Image-Based Drug Screening in Human Blood for Personalized Medicine
Permission from lecturers required for all students. Block course in the 1st quarter of the autumn semester.
  • Tue 12:45-16:30 (HPM E 28)
  • Wed 07:45-16:30 (HPM E 28)
  • Thu 07:45-16:30 (HPM E 28)
  • Fri 07:45-16:30 (HPM E 28)
100 h semesterly

Offered In