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Nanoscale Molecular Imaging
Last Updated: 2026-02-05 16:08:07
Abstract
This course will provide comprehensive knowledge about the principal analytical techniques for nanoscale molecular imaging as well their practical applications. In addition to the fundamental concepts, the students will also learn to apply the advanced molecular characterization tools to solve problems in the chemical, biological and material sciences.
Objective
This course will provide comprehensive knowledge about the principal analytical techniques for nanoscale molecular imaging as well their practical applications. In addition to the fundamental concepts, the students will also learn to apply the advanced molecular characterization tools to solve problems in the chemical, biological and material sciences.
Content
Nanoscale molecular imaging using fluorescence spectroscopy -Structured Illumination Microscopy (SIM) -Stimulated Emission Depletion Microscopy (STED) -Direct stochastic optical reconstruction microscopy (dSTORM) -Photoactivated localization microscopy (PALM) Nanoscale molecular imaging using Raman spectroscopy -Scanning near-field optical microscopy (aperture SNOM) -Tip-enhanced Raman spectroscopy (TERS): Based on both atomic force microscopy (AFM) & scanning tunnelling microscopy (STM) Nanoscale molecular imaging using infra-red (IR) spectroscopy -Nanoscale Fourier-transform Infrared Spectroscopy (Nano-FTIR) -Tapping AFM-IR -Photothermal AFM-IR Nanoscale molecular imaging using ions -Nanoscale secondary ion mass spectrometry (NanoSIMS) Single molecule imaging techniques -Scanning probe microscopy: STM & AFM -Ultrahigh vacuum (UHV)-TERS -Cryogenic electron microscopy (Cryo-EM)
Resources
Lecture Notes
Lecture notes will be made available online.
Literature
Information about relevant literature will be available in the lecture & in the lecture notes.
General Information
- Language
- English
- Levels
- MSC
- Frequency
- Yearly recurring
Examination
- Type
- session examination
- Mode
- oral 20 minutes
Course Components
| Type | Title | Time & Place | Hours |
|---|---|---|---|
| lecture with exercise | Nanoscale Molecular Imaging |
|
2 h weekly |
Offered In
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Recommended Elective Courses (These courses are particularly recommended for the Bioimaging track. Please consult your track adviser if you wish to select other subjects.)
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Recommended Elective Courses (These courses are particularly recommended for the Biomechanics track. Please consult your track adviser if you wish to select other subjects.)
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Elective Courses (The students are free to choose individually from the entire course offer of ETH Zürich on the Master level. Please consult the study administration in case of questions.)
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Electives (Students are free to choose from a range of D-CHAB chemistry courses appropriate to their level of study (please note admission requirements). In case of doubt, contact the student administration.)
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