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529-0241-00L 6 Credits
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Modern Asymmetric Synthesis

Moderne Methoden der Asymmetrischen Synthese

Lecturers & Examiners: Prof. Dr. Erick M. Carreira
VVZ CR n/a

Last Updated: 2026-02-05 14:55:01

Abstract

Advanced Modern Methods of Asymmetric Synthesis and their Application in Natural Product Total Syntheses.

Objective

Knowledge of modern methods in asymmetric stereocontrol and enantioselective catalysis.

Content

Preparation and reactivity of oxonium/iminium species, chiral acetals in synthesis; Conformational analysis of macrocyclic rings, macrocyclic stereocontrol; Asymmetric catalysis: introduction, mechanistic analyses, catalyst- and ligand design, control elements, substrate activation, important asymmetric catalytic reactions with special focus on synthesis; Enolate alkylation, directed reactions; Allylic substitution reactions; The Chiron approach; Discussion of the key steps in selected, recent total syntheses in the context of diastereoselective synthesis and asymmetric catalysis.

General Information

Language
English
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 60 minutes, oral 30 minutes
Aids
keine

Course Components

Type Title Time & Place Hours
lecture with exercise Moderne Methoden der Asymmetrischen Synthese No time listed 3 h weekly

Offered In