VVZ API is not affiliated with ETH Zurich. Data might be outdated or incorrect. Please view the official ETHZ Vorlesungsverzeichnis for binding information.

376-0009-00L 6 Credits BSC D-HEST , D-BIOL
You're viewing possible stale or outdated data. Please check the latest semester for more up-to-date information.

Molecular and Cell Biology in Health and Disease

Molekular- und Zellbiologie in Gesundheit und Krankheit

Lecturers & Examiners: Dr. Christian Wolfrum
VVZ CR n/a

Last Updated: 2026-02-05 16:07:11

Abstract

The course will focus on the biochemical, molecular and cellular mechanisms governing disease development. It will cover different areas building on the courses Molecular Genetics and Cell Biology as well as Biochemistry to develop a conceptual understanding of these processes.

Objective

Understand the molecular and cellular concepts of disease development based on examples of different diseases and physiological adaptations. Understand the molecular and cellular changes responsible for a selected number of diseases/physiological adaptations. Develop a presentation explaining the molecular and cellular changes responsible for a specific disease/physiological adaptation.

Content

1. linear mechanistic models of pathological processes & collagen and its pathological processes 2. protein diseases - mutations/aggregates 3. enzymes in pathology - enzyme deficiency, drug targets, drug interactions, biomarkers 4. biochemical methods in diagnostics 5. biological membranes - lipid-dependent diseases lipid metabolism, cholesterol metabolism, cholesterol in the nervous system, membrane diseases in the nervous system 6. protein-mediated movement - proteins as motor function, muscle diseases, myotonia, cardiomyophathies 7. cellular communication - principle of hormonal effects, thyroid, beta cell, insulin, diabetes, adipokines 8. hypertension - regulation of blood pressure 9. metabolism - carbohydrate metabolism and related diseases 10. metabolism - hereditary fructose intolerance, glycogen storage disorders 11. disorders of amino acid metabolism, urea cycle, gout 12. systemic regulation metabolism autophagy

Resources

Literature

Löffler/Petrides: Biochemie und Pathobiochemie.

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 120 minutes
Aids
None
Digital
The exam takes place on devices provided by ETH Zurich.
Obligatorisches Leistungselement: Abgabe einer Gruppenpräsentation bis 13.05.2022. Diese Gruppenpräsentation wird benotet und trägt mit 25% zur Gesamtnote bei.Die Teilnahme am Abschluss-Symposium am 20.05.2022 ist freiwillig und wird mit 0.25 Bonuspunkten vergütet.

Course Components

Type Title Time & Place Hours
lecture with exercise Molekular- und Zellbiologie in Gesundheit und Krankheit
Die Vorlesungen finden am Donnerstag 12-16h statt. Die Übungen finden jeweils an folgenden Freitagen von 08-10h statt: 04.03./11.03./18.03./29.04./06.05./13.05.2022. Abschluss-Symposium am 20.05.2022
  • Thu 12:15-14:00 (HG G 3)
  • Thu 14:15-16:00 (HG G 3)
  • Fri 07:45-09:30 (HCI D 4)
  • Fri 07:45-09:30 (HCI E 2)
  • Fri 07:45-09:30 (HCI E 8)
  • Fri 07:45-09:30 (HCI F 8)
  • Fri 07:45-09:30 (HCI J 8)
  • Fri 07:45-09:30 (HIT J 51)
  • Fri 07:45-09:30 (HIT J 52)
  • Fri 07:45-09:30 (HIT J 53)
  • Fri 08:00-09:45 (Y16 G 05)
  • Fri 08:00-09:45 (Y35 F 32)
  • 11.03 Date 08:45-10:30 (HCI D 4)
  • 18.03 Date 08:45-10:30 (HCI D 4)
  • 29.04 Date 08:45-10:30 (HCI D 4)
  • 06.05 Date 08:45-10:30 (HCI D 4)
  • 13.05 Date 08:45-10:30 (HCI D 4)
5 h weekly

Offered In