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535-0240-00L 2 Credits BSC D-CHAB
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Laboratory Course in Biopharmacy

Praktikum Biopharmazie

Lecturers & Examiners: Prof. Stefanie-Dorothea Krämer
Bedingungen: Gleichzeitige oder vorgängige Belegung und Besuch der Vorlesung, Praktikum Pharmazeutische Analytik bestanden.
VVZ CR n/a

Last Updated: 2026-02-05 16:06:45

Abstract

Experimental determination of pharmacokinetic parameters in vitro: biotransformation experiments (phase I and II) with rat liver microsomes; determination of partition coefficients in the octanol/buffer system including stability testing; protein binding and displacement studies with bovine serum albumin as binding partner.

Objective

Consolidation and implementation of the lecture "Biopharmazie" (535-0241-00 V).

Content

Experimental determination of pharmacokinetic parameters in vitro: biotransformation experiments (phase I and II) with pork liver microsomes; determination of partition coefficients in the octanol/buffer system including stability testing; protein binding and displacement studies with bovine serum albumin as binding partner.

Resources

Lecture Notes

Biopharmazie Praktikumsskript (Krämer/Wunderli-Allenspach)

Literature

P. Langguth, G. Fricker, H. Wunderli-Allenspach "Biopharmazie", Wiley-VCH Verlag, Weinheim, 2004

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
ungraded semester performance

Course Components

Type Title Time & Place Hours
practical/laboratory course Praktikum Biopharmazie
Permission from lecturers required for all students. Das Praktikum dauert 3 Wochen, Gemäss separatem Plan.
No time listed 60 h semesterly

Offered In