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551-0434-00L 6 Credits BSC D-BIOL
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NMR Spectroscopy in Biology

Lecturers: Prof. Dr. Kurt Wüthrich, Prof. Dr. Frédéric Allain, Dr. Alvar Diego Gossert
Examiners: Prof. Dr. Frédéric Allain
Number of participants limited to 6. The enrolment is done by the D-BIOL study administration.
VVZ CR n/a

Last Updated: 2026-02-05 16:08:10

Abstract

In this block course, students actively participate in ongoing research projects in the research groups of Profs. Allain, Wüthrich and Dr. Gossert. The students will be tutored in their experimental work by experienced postdoc students. In addition, the course includes specific lectures that provide the theoretical background for the experimental work, as well as exercises and literature work.

Objective

The course provides first "hands on" insight into applications of NMR spectroscopy in biological sciences. The course should enable the students to understand the potential and limitations of NMR applied to biological problems.

Content

The topics include studies of proteins, RNA and protein-RNA interactions, Participation in one of the following projects will be possible: - NMR of RNA - NMR of several protein-RNA complexes (hnRNPF, nPTB, SR proteins) - NMR studies of protein-ligand interactions - dynamics of protein-RNA complexes - Segmental isotopic labeling to study multidomain proteins - NMR Methods Development

Resources

Lecture Notes

No script

Literature

Lists of individual reading assignments will be handed out.

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
graded semester performance
Es wird nur der hauptverantwortliche Examinator aufgeführt. Weitere Examinatoren: Die oben aufgeführten Dozierenden.Students are obliged to be present throughout the block course.Cancellation: If you have to deregister from a course that has been assigned to you (just emergency reasons), please notify in written the course coordinator at least four weeks before the course starts, for courses in the 1st quarter, a cancellation period of one week applies. The study secretariat D-BIOL must also be informed (email CC [email protected]) so that the enrollment is deleted. Otherwise the course is considered as "failed".

Course Components

Type Title Time & Place Hours
practical/laboratory course NMR Spectroscopy in Biology
Permission from lecturers required for all students. Block course in the 2nd quarter of the spring semester
  • Tue 12:45-16:30 (HPP L 21)
  • Wed 07:45-16:30 (HPP L 21)
  • Thu 07:45-16:30 (HPP L 21)
  • Fri 07:45-16:30 (HPP L 21)
100 h semesterly

Offered In