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551-0128-00L 8 Credits BSC D-CHAB , D-BIOL
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Fundamentals of Biology I

Grundlagen der Biologie I

Registrations via myStudies until 29.1.2021 at the latest. Subsequent registrations will not be considered. General safety regulations: -Whenever possible the distance rules have to be respected. -All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed. -The installation and activation of the Swiss Covid-App is highly encouraged. -Any additional rules for individual courses have to be respected. -Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible.
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Last Updated: 2026-02-05 15:53:57

Abstract

This 1st year Laboratory course introduces the students to the basic experimental techniques used in the classical and modern molecular biosciences. In the first year (Praktikum GL BioI) the students will be introduced into the basic concept and methods of Microbiology, Biochemistry and Molecular Biology in 12 consecutive course days.

Objective

Introduction to biology with practical work. General Praktikum-information and course material can be obtained from Moodle The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail).

Content

This 1st year Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. Students will participate in 12 consecutive course days. Because of necessary Covid-19 safety measures the practical will operate in two shifts to reduce the number of student in the practical rooms. 1. shift 8:00-13:00 2. shift 13:30-18:30 Program Day 1: Isolation and cultivation of microorganisms Day 2: Morphological, biochemical and genetic characterization of microorganisms Day 3: Evolution of microorganisms and their abiotic and biotic interactions Day 4: Lifestyle of fungi as eukaryotic representatives of the microorganisms Day 5: DNA extraction, tranformation (E.coli, yeast) Day 6: RNA extraction, Life cycle of eukaryotic cells Day 7: Purification of TAQ polymerase from E coli by ionexchange chromatography Day 8: Characterizing fractions of the purification of TAQ polymerase (SDS-PAGE, WB) Day 9: mRNA splicing in yeast by RT-PCR and purified TAQ polymerase Day 10: Affinity chromatography, protein crystallization and structure Day 11: Protein folding, protein stability and Enzyme kinetics Day 12: Protein folding, protein stability and Enzyme kinetics

Resources

Lecture Notes

Laboratory manuals can be downloaded from Moodle

Learning Materials (Links)

General Information

Language
German
Levels
BSC
Frequency
Yearly recurring

Examination

Type
ungraded semester performance
Ihre Anwesenheit ist an allen 12 Praktikumstagen obligatorisch. Abwesenheiten werden nur bei Vorliegen eines ärztlichen Attests akzeptiert. Über Ausnahmen in besonders dringenden Fällen entscheidet der Studiendelegierte des D-BIOL.

Registration & Places

Max Places
300
Signup End
29.01.2021

Course Components

Type Title Time & Place Hours
practical/laboratory course Grundlagen der Biologie I
Das Praktikum wird durch alle Professoren des Departements Biologie unterstützt und durchgeführt. Das Praktikum wird aufgrund notwendiger Sicherheitsmassnahmen wegen Covid-19 im FS21 ausnahmsweise am Donnerstag und am Freitag in zwei Schichten (1. Schicht 8:00-13:00 und 2. Schicht 13:30-18:30) durchgeführt. Studiengänge Biochemie-Chemische Biologie BSc und Interdisziplinäre Naturwissenschaften BSc Donnerstag Studiengänge Biologie BSc und Pharmazeutische Wissenschaften BSc Donnerstag oder Freitag je nach Gruppeneinteilung
  • Thu 07:45-18:30 (HCI E 374)
  • Thu 07:45-18:30 (HCI E 378)
  • Thu 07:45-18:30 (HCI E 392)
  • Thu 07:45-18:30 (HCI E 396)
  • Fri 07:45-18:30 (HCI E 374)
  • Fri 07:45-18:30 (HCI E 378)
  • Fri 07:45-18:30 (HCI E 392)
  • Fri 07:45-18:30 (HCI E 396)
8 h weekly

Offered In