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529-0042-00L 4 Credits BSC , DR D-CHAB
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Structure Elucidation by NMR

Lecturers & Examiners: Dr. Marc-Olivier Ebert
VVZ CR n/a

Last Updated: 2026-02-05 15:53:42

Abstract

Structure Elucidation of Complex Organic Molecules by NMR

Objective

Structure elucidation of complex organic molecules (including peptides, oligosaccharides and oligonucleotides) by advanced 1D and 2D NMR spectroscopy. The emphasis of the course is on the selection of optimal strategies for the solution of a given problem, spectrum interpretation and possible artifacts. Solving and discussing practical case studies/problems demonstrating the individual methods and, in the last third of the course, the combined application of several methods form an important part of the course.

Content

Structure determination by multi-pulse and 2D NMR spectroscopy. Homonuclear and heteronuclear shift correlation through scalar coupling; one and two dimensional methods based on the nuclear Overhauser effect. Choosing the best strategy for a given problem, interpretation and artefacts.

Resources

Lecture Notes

Scripts (in English) are distributed in the course

Literature

"T.D.W. Claridge, High Resolution NMR Techniques in Organic Chemistryî, Pergamon Press, 1999. (NMR Teil) Further reading and citations are listed in the script.

General Information

Language
English
Levels
BSC , DR
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 60 minutes
Aids
Alle, ausser Telekommunikation und Computer, Taschenrechner erlaubt
Schriftliche Prüfung auf Englisch, Antwort auf Deutsch möglich.

Course Components

Type Title Time & Place Hours
lecture with exercise Structure Elucidation by NMR
  • Tue 07:45-09:30 (HCI D 2)
2 h weekly

Offered In