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529-0231-00L 4 Credits BSC D-CHAB
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Organic Chemistry III: Introduction to Asymmetric Synthesis

Lecturers & Examiners: Prof. Dr. Erick M. Carreira
VVZ CR n/a

Last Updated: 2026-02-05 15:47:20

Abstract

Methods of Asymmetric Synthesis

Objective

Understanding of the basic principles of diastereoselective synthesis

Content

Conformational analysis: acyclic and cyclic systems; Diastereoselective sigmatropic rearrangements; Diastereoselective Carbonyl addition reactions: Cram- and Felkin-Anh models, carbonyl Lewis acid interactions, chelate controlled reactions; chemistry of enolates, selective formation; asymmetic enolate alkylation; aldol reactions, allyl- and crotyl-metal chemistry; cyclisations, Baldwin rules; Diastereoselective olefin functionalization: hydroboration, dihydroxylation, epoxidation.

Resources

Literature

E. M. Carreira and L. Kvaerno Classics in Stereoselective Synthesis, Wiley-VCH 2009 Evans' Problems in Organic Chemistry App

General Information

Language
English
Levels
BSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
written 60 minutes, oral 30 minutes
Aids
Keine

Course Components

Type Title Time & Place Hours
lecture with exercise Organic Chemistry III: Introduction to Asymmetric Synthesis
  • Wed 07:45-10:30 (HCI D 4)
  • Wed 07:45-10:30 (HCI D 6)
  • Wed 07:45-10:30 (HCI E 2)
  • Wed 07:45-10:30 (HCI F 2)
  • Wed 07:45-10:30 (HCI F 8)
  • Wed 07:45-10:30 (HCI J 7)
  • Wed 07:45-10:30 (HCI J 8)
3 h weekly

Offered In