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529-0004-01L 6 Credits BSC , MSC D-BSSE , D-INFK , D-CHAB , D-BIOL , D-MATH
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Classical Simulation of (Bio)Molecular Systems

VVZ CR n/a

Last Updated: 2026-02-05 15:36:13

Abstract

Molecular models, classical force fields, configuration sampling, molecular dynamics simulation, boundary conditions, electrostatic interactions, analysis of trajectories, free-energy calculations, structure refinement, applications in chemistry and biology. Exercises: hands-on computer exercises for learning progressively how to perform an analyze classical simulations (using the package GROMOS).

Objective

Introduction to classical (atomistic) computer simulation of (bio)molecular systems, development of skills to carry out and interpret these simulations.

Content

Molecular models, classical force fields, configuration sampling, molecular dynamics simulation, boundary conditions, electrostatic interactions, analysis of trajectories, free-energy calculations, structure refinement, applications in chemistry and biology. Exercises: hands-on computer exercises for learning progressively how to perform an analyze classical simulations (using the package GROMOS).

Resources

Lecture Notes

Script booklet (copies of powerpoint slides) distributed at the first or second lecture.

Literature

See: www.csms.ethz.ch/education/CSBMS

Learning Materials (Links)

General Information

Language
English
Levels
BSC , MSC
Frequency
Yearly recurring

Examination

Type
session examination
Mode
oral 30 minutes

Course Components

Type Title Time & Place Hours
lecture with exercise Classical Simulation of (Bio)Molecular Systems
2 hr lecture + 2 hr exercise session in our computer room; the students can choose between two alternative exercise sessions, either on Tuesdays 7:30-9:30 a.m. or on Thursdays 7:45-9:45 a.m.; the course was previously named CSCBP (the content remains the same, but the new title is more adequate)
  • Tue 10:00-12:00 (ON LI NE)
4 h weekly

Offered In