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529-0733-01L 6 Credits MSC D-BSSE , D-INFK , D-CHAB , D-BIOL

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Enzymes

Lecturers & Examiners: Prof. em. Dr. Donald Hilvert

VVZ CR n/a

Last Updated: 2026-02-05 15:36:13

Abstract

Principles of enzymatic catalysis, enzyme kinetics, mechanisms of enzyme-catalyzed reactions (group transfer reactions, carbon-carbon bond formation, eliminations, isomerisations and rearrangements), cofactor chemistry, enzymes in organic synthesis and the biosynthesis of natural products, catalytic antibodies.

Objective

Overview of enzymes, enzyme-catalyzed reactions and metabolic processes.

Content

Principles of enzymatic catalysis, enzyme kinetics, mechanisms of enzyme catalyzed reactions (group transfer reactions, carbon-carbon bond formation, eliminations, isomerisations and rearrangements), cofactor chemistry, enzymes in organic synthesis and the biosynthesis of natural products, catalytic antibodies.

Resources

Lecture Notes

A script will not be handed out.

Literature

General: T. Bugg, An Introduction to Enzyme and Coenzyme Chemistry, Blackwell Science Ltd., Oxford, 1997. In addition, citations from the original literature relevant to the individual lectures will be assigned weekly.

General Information

Language: English
Levels: MSC
Frequency: Yearly recurring

Examination

Type: session examination
Mode: written 60 minutes, oral 20 minutes
Aids: Keine

Course Components

Type	Title	Time & Place	Hours
lecture with exercise	Enzymes Lecture 2 hours on Monday, 09:45 - 11:30. First lecture will be held exceptionally on Tuesday 15.09.2020, 11:45. 1 hour exercise Monday or Tuesday from second week on - according to agreement.	Mon 08:45-09:30 (HCI H 8.1) Mon 09:45-11:30 (HCI J 4) Tue 11:45-12:30 (HCI H 2.1) 15.09 Date 11:45-12:30 (HCI G 3)	3 h weekly

Offered In

Chemistry Master
- Electives (Students are free to choose from a range of D-CHAB chemistry courses appropriate to their level of study (please note admission requirements). In case of doubt, contact the student administration.)
  - Biological Chemistry
Biology Master
- Elective Major Subject Areas
Computational Biology and Bioinformatics Master (More informations at: )
- Advanced Courses (A total of 30 ECTS needs to be acquired in the Advanced Courses category. Thereof 18 ECTS in the Theory and 12 ECTS in the Biology category. Note that some of the lectures are being recorded: )
  - Biology (At least 12 ECTS need to be acquired in this category.)